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Estimate creatinine clearance using Cockcroft-Gault, with CKD stage ranges.
Creatinine clearance (CrCl) is an estimate of kidney filtration rate calculated using the Cockcroft-Gault equation from age, weight, serum creatinine, and sex. It is used to assess kidney function and adjust drug dosages.
⚠️ Educational use only. Always consult a healthcare provider for kidney function assessment and medication dosing.
| Stage | GFR (mL/min) | Description |
|---|---|---|
| 1 (Normal) | ≥ 90 | Normal kidney function |
| 2 (Mild) | 60 to 89 | Mildly decreased function |
| 3a (Mild-Moderate) | 45 to 59 | Mild to moderate decrease |
| 3b (Moderate-Severe) | 30 to 44 | Moderate to severe decrease |
| 4 (Severe) | 15 to 29 | Severely decreased function |
| 5 (Failure) | < 15 | Kidney failure (dialysis) |
Formula
CrCl (mL/min) = ((140 − Age) × Weight (kg)) ÷ (72 × Serum Creatinine (mg/dL)) [× 0.85 if female]Age = Patient age in years
Weight = Actual body weight in kilograms
Serum Creatinine = Blood creatinine level in mg/dL
Worked Example
50-year-old male, 70 kg, creatinine 1.0 mg/dL
Did you know? Approximately 37 million Americans have chronic kidney disease, but 9 out of 10 don't know it because early stages often have no symptoms. CrCl estimation is crucial for early detection (source: National Kidney Foundation).
Sources
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